Houston Astros vs Texas Rangers Prediction, Odds and Picks for Today, 05/27/26

After being held hitless in the series-opener on Monday, the Rangers responded in a major way with a 10-7 win over the Astros on Tuesday. Texas plated 8 runs in the 1st inning of Tuesday’s contest, and are now looking to keep the momentum going in Wednesday night’s meeting. Texas will send Jacob deGrom to the mound, and he is having a forgettable May so far. deGrom enters this matchup with a 6.45 ERA over 4 May starts, and not surprisingly, the Rangers are just 1-3 in those outings. The Astros have scored 8, 9, and 7 runs over their last 3 games, so deGrom could have his hands full in this one.

Despite Tuesday’s loss, the Astros still carry plenty of momentum into this contest. Houston has won 4 of its last 5 games, and is 5-3 so far on it’s current extended road trip. On the other side, the Rangers have won just once over their last 5 games and continue to be an up-and-down team this season. Furthermore, Texas’ team OPS of .618 at home is the lowest mark in all of baseball. That alone make this Rangers team tough to trust against anyone right now, but especially against an Astros team that is having a solid road trip. Back the Astros +1.5 on the run line.

Astros vs Rangers prediction: Astros +1.5 (-155) available at time of publishing. Playable to -160.