Seattle Mariners vs Houston Astros Prediction, Odds and Picks for Today, 05/12/26

The Seattle Mariners will be in Houston on Tuesday for the second game of their series against the Astros. The Mariners will be looking to make it two wins in a row against the Astros. The Mariners offense has not been great this season; however, their pitching and defense has kept them in most games. On Tuesday they will be sending Bryan Woo to the mound. Despite an up and down season, he is coming off an electric start where he only gave up one hit over 6.0 innings and struck out nine batters. This is more like the Bryan Woo we have come to expect over the years. The Astros on the other hand, are second-last in the MLB averaging 5.6 runs allowed per game. They are giving the ball to Tatsuya Imai who is making his return from the injured list. His last outing on April 10^th of this year came against the Mariners, he only recorded one out, walked four batters and gave up three runs. Expect him to be rusty and the Mariners to have some confidence against him. The pitching advantage is with the Mariners in this matchup, and their offense is good enough to keep pace with the Astros. Give me Seattle in this one.

Mariners vs Astros prediction: Mariners ML (-155) available at time of publishing. Playable to -160.

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