Seattle Mariners vs Kansas City Royals Prediction, Odds and Picks for Today, 05/22/26

The Seattle Mariners are in Kansas City to take on the Royals on Friday night. The Mariners will hand the ball to right-hander Logan Gilbert, and he is coming off a forgettable start in which he allowed 7 earned runs on 5 hits over 6.2 innings against the Padres. However, that outing is definitely an outlier for Gilbert this season. He has allowed 3 earned runs or fewer in 7 of his 10 starts, and he’s been sensational on the road. Gilbert’s ERA drops from 5.67 at home to 1.59 when pitching on the road. Furthermore, his BAA drops from .265 to .203. The Royals have been among the worst offenses in baseball so far this season, so Gilbert seems to have a favorable matchup to bounce back in this one.

Kansas City will send left-hander Noah Cameron to the mound, and he seems to have a favorable matchup against Seattle’s lineup. The Mariners own a lowly .189 team batting average against lefties this season, which is the lowest mark in all of baseball. In addition, their .595 team OPS against southpaws ranks 29th. Cameron isn’t on fire right now, but he should be able to limit the damage from the visiting Mariners in this one. With a total of 8, look to the under.

Mariners vs Royals prediction: Under 8 (-105) available at time of publishing. Playable to -110.