St. Louis Cardinals vs Milwaukee Brewers Prediction, Odds and Picks for Today, 05/25/26

The St. Louis Cardinals and Milwaukee Brewers get a series started on Monday afternoon. The Brewers dropped 2 of 3 to the Dodgers over the weekend, while the Cardinals battled the weather in Cincinnati, ultimately raining out Sunday’s contest. American Family Field has a roof though, so no worries on Monday afternoon. Monday is a Miz day as Jacob Misiorowski takes the ball for the Brew Crew. This game comes down to whether you think Miz will continue to do amazing things, and I am not betting against that. So give me the Brewers on the Run Line at -1.5.

Misiorowski is doing incredible things. He has a 1.89 ERA and a WHIP of just 0.88, and he has 88 Ks in just 57 innings. He is virtually untouchable, hasn’t given up a run all month, and has struck out at least 8 guys in 6 straight games. Oh, and something like the fastest 80 or so pitches thrown by starters this season are all by Miz, and he is routinely hitting 102 or 103. Good luck hitting him. On the other side is Matthew Libertore, who is having a fine season, but he has logged two straight short outings while allowing 4 runs. This game comes down to whether the Brewers show up on offense, and whether you want to bet on the Miz finally coming back to earth a bit. I’ll ride the hot hand.

Cardinals vs Brewers Prediction: Brewers -1.5 (-110) available at the time of publishing. Playable to -120.