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HomeNFLNFL PredictionsCleveland Browns vs Detroit Lions Prediction, Odds and Picks

Cleveland Browns

Cleveland Browns vs Detroit Lions Prediction, Odds and Picks for Sunday, 09/28/25

Updated: 5:00 AM ET Sep 29, 2025

Ford FieldFOX

1-2

Browns

1:00 PM ETSun Sep 28

2-1

Lions

Detroit Lions

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Caleb Wilfinger

Updated: 5:00 AM ET September 29, 2025

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Deputy Editor for Pickswise with years of experience handicapping and giving out winning picks. Lover of all US sports and Southampton FC. For Caleb Wilfinger media enquiries, please email contact@pickswise.com.

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