Below you will find our NFL week 2 picks against the spread and straight up for every game this week. Read our expert’s in-depth NFL week 2 predictions for the best wagers of the second week of the NFL. Head on over to our NFL parlays page to see our combined picks for week 2 or our NFL odds page to make sure you get the best price on your wager.
The home of our free NFL Picks and Predictions for week 2 of the 2022/23 NFL season.
Our expert NFL handicappers research the entire NFL Week 2 schedule, leaving no stone unturned to bring you the best NFL expert picks across the week 2 slate.
We take a look through all of the week 2 NFL games, bring you the entire schedule, including the week 2 spreads, betting lines, and money line favorites and our week 2 NFL picks and predictions will encompass all of these popular NFL Betting lines, alongside our match previews and analysis.
Los Angeles Chargers at Kansas City Chiefs
Spread Pick: Chargers +4.5
Miami Dolphins at Baltimore Ravens
Spread Pick: Ravens -3.5
New York Jets at Cleveland Browns
Spread Pick: Browns -5.5
Washington Commanders at Detroit Lions
Spread Pick: Lions -1.5
Indianapolis Colts at Jacksonville Jaguars
Spread Pick: Colts -4
Tampa Bay Buccaneers at New Orleans Saints
Spread Pick: Buccaneers -2.5
Carolina Panthers at New York Giants
Spread Pick: Giants -2
New England Patriots at Pittsburgh Steelers
Spread Pick: Steelers +2
Atlanta Falcons at Los Angeles Rams
Spread Pick: Rams -10.5
Seattle Seahawks at San Francisco 49ers
Spread Pick: 49ers -9.5
Cincinnati Bengals at Dallas Cowboys
Spread Pick: Bengals -7
Houston Texans at Denver Broncos
Spread Pick: Broncos -9.5
Arizona Cardinals at Las Vegas Raiders
Spread Pick: Cardinals +6
Chicago Bears at Green Bay Packers
Spread Pick: Packers -10
Tennessee Titans at Buffalo Bills
Spread Pick: Titans +10
Minnesota Vikings at Philadelphia Eagles
Spread Pick: Vikings +2.5
Thursday, Sept. 15
Los Angeles Chargers at Kansas City Chiefs, 8:20 p.m. (Thursday Night Football)
Sunday, Sept. 18
Miami Dolphins at Baltimore Ravens, 1 p.m.
New York Jets at Cleveland Browns, 1 p.m.
Washington Commanders at Detroit Lions, 1 p.m.
Indianapolis Colts at Jacksonville Jaguars, 1 p.m.
Tampa Bay Buccaneers at New Orleans Saints, 1 p.m.
Carolina Panthers at New York Giants, 1 p.m.
New England Patriots at Pittsburgh Steelers, 1 p.m.
Atlanta Falcons at Los Angeles Rams, 4:05 p.m.
Seattle Seahawks at San Francisco 49ers, 4:05 p.m.
Cincinnati Bengals at Dallas Cowboys, 4:25 p.m.
Houston Texans at Denver Broncos, 4:25 p.m.
Arizona Cardinals at Las Vegas Raiders, 4:25 p.m.
Chicago Bears at Green Bay Packers, 8:20 p.m. (Sunday Night Football)
Monday, Sept. 19
With many different NFL betting sites available, it’s important to shop the odds and lines each game week. Check out the best NFL Week 2 odds from the Top Online Sportsbooks below. You can find all of the NFL week 2 Money line odds, Week 2 NFL Spreads, and Week 2 NFL Total’s.
Check out the NFL Week 2 Spreads and Money Line favorites at all of the best online sportsbooks below.
Thursday Night Football gets the NFL Week 2 schedule off to a bang. Two faces of the league in Patrick Mahomes and Justin Herbert headlining was will be an extremely important AFC West Matchup. Both teams have been touted by experts as ones that could go all the way this season, so who will take the early advantage in the division.