NFL Week 1 Picks, Predictions & Betting Lines

The home of our free Week 1 NFL Picks and Predictions. Our expert NFL handicappers research the entire NFL Week 1 schedule, to bring you the best NFL expert picks this week. For full expert analysis, insight, and all of our Week 1 NFL picks and Predictions, be sure to check out some of our most popular NFL pages including our NFL Picks, and NFL Predictions, alongside our NFL Prop Bets and NFL Parlays today.

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Thursday, Sept. 7Spread Pick
Detroit Lions vs. Kansas City ChiefsLions +6.5
Sunday, Sept. 10Spread Pick
Carolina Panthers vs. Atlanta FalconsFalcons -3.5
Tampa Bay Buccaneers vs. Minnesota VikingsVikings -6
Cincinnati Bengals vs. Cleveland BrownsBrowns +2.5
Jacksonville Jaguars vs. Indianapolis ColtsJaguars -5
San Francisco 49ers vs. Pittsburgh SteelersSteelers +2.5
Tennessee Titans vs. New Orleans SaintsSaints -3
Arizona Cardinals vs. Washington CommandersCardinals +7
Houston Texans vs. Baltimore RavensRavens -10
Philadelphia Eagles vs. New England PatriotsEagles -4
Las Vegas Raiders vs. Denver BroncosRaiders +3.5
Miami Dolphins vs. Los Angeles ChargersChargers -3
Los Angeles Rams vs. Seattle SeahawksRams +5
Green Bay Packers vs. Chicago BearsPackers +1.5
Dallas Cowboys vs. New York GiantsCowboys -3.5
Monday, Sept. 11Spread Pick
Buffalo Bills vs. New York JetsBills -2.5

NFL Odds Week 1 

With many different NFL betting sites available, it’s important to shop the odds and lines each game week. Check out the best NFL Week 1 odds from the Top Online Sportsbooks below. You can find all of the NFL Week 1 Money line odds, Week 1 NFL Spreads, and Week 1 NFL Total’s.

NFL Week 1 Spreads, Money Line Odds & Over Under Points Totals

Check out the NFL Week 1 Spreads and Money Line favorites at all of the best online sportsbooks below.

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