NFL Week 16 Picks, Predictions & Betting Lines

Below you will find our NFL week 16 picks against the spread and straight up for every game this week. Read our expert’s in-depth NFL week 16 picks for the best wagers of the sixteenth week of the NFL. Head on over to our NFL parlays page to see our combined picks for week 16 or our NFL odds page to make sure you get the best price on your wager.

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The home of our free NFL Picks for week 16 of the 2022/23 NFL season.

Our expert NFL handicappers, research the entire NFL Week 16 schedule, leaving no stone unturned to bring you the best NFL expert picks across the week 16 slate.

We take a look through all of the week 16 NFL games, bring you the entire schedule, including the week 16 spreads, betting lines, and Moneyline favorites and our week 16 NFL picks and predictions will encompass all of these popular NFL Betting lines, alongside our match previews and analysis.

NFL Week 16 Schedule –  NFL Games Week 16  

Thursday, Dec. 22

Jacksonville Jaguars at New York Jets, 8:15 p.m. (Thursday Night Football)

Saturday, Dec. 24

Atlanta Falcons at Baltimore Ravens, 1 p.m.
Detroit Lions at Carolina Panthers, 1 p.m.
Buffalo Bills at Chicago Bears, 1 p.m.
New Orleans Saints at Cleveland Browns, 1 p.m.
Seattle Seahawks at Kansas City Chiefs, 1 p.m.
New York Giants at Minnesota Vikings, 1 p.m.
Cincinnati Bengals at New England Patriots, 1 p.m.
Houston Texans at Tennessee Titans, 1 p.m.
Washington Commanders at San Francisco 49ers, 4:05 p.m.
Philadelphia Eagles at Dallas Cowboys, 4:25 p.m.
Las Vegas Raiders at Pittsburgh Steelers, 8:15 p.m. (Saturday Night Football)

Sunday, Dec. 25 (Christmas)

Green Bay Packers at Miami Dolphins, 1 p.m.
Denver Broncos at Los Angeles Rams, 4:30 p.m.
Tampa Bay Buccaneers at Arizona Cardinals, 8:20 p.m. (Sunday Night Football)

Monday, Dec. 26

Los Angeles Chargers at Indianapolis Colts, 8:15 p.m. (Monday Night Football)

NFL Odds Week 16  

Our experts take a  complete look at all of the NFL odds for Week 16. The balance between a confident  NFL pick and good value odds is an important one, so taking a look at the Week 16 NFL odds is always important ahead of making your NFL Week 16 picks or wagers.

With many different NFL betting lines to focus on in any given match, we take a look at the main three, most popular markets in the NFL week 16 Moneyline odds, Spreads, and Totals.

The NFL Week 16 Odds will appear here once the Week 16 odds have been set and are available at the Top Online Sportsbooks.

NFL Week 16 Spreads And Money Line Favorites 

NFL Week One Spreads And Moneyline Odds Favorites

Check out the NFL Week 16 Spreads and Money Line favorites at all of the  best online sportsbooks below.


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