Cleveland Guardians vs Detroit Tigers Prediction, Odds and Picks for Today, 05/20/26

The Guardians and Tigers continue their 4-game divisional series on Wednesday after the Guards took the first 2 games, extending this terrible losing streak for Detroit. In fact, the Tigers have lost 4 in a row, as well as 7 of their last 9, and they are 4-13 SU in the month of May. Meanwhile, Cleveland is on a 4-game winning streak, while they have won 10 of their last 13 games. 

Fortunately for the Tigers, they will face Tanner Bibee today. Bibee has yet to pick up a win (0-6), and the Guards have lost every single game in which he started – 10 in total – except his very first of the season. That said, this Tigers lineup is hitting just .242 against Bibee in 132 career plate appearances. As for Detroit, a pitcher has not been announced just yet, but given the injuries to the pitching staff, I expect it to be a bullpen day or a call-up getting a spot start. 

Given the unknown of Detroit’s pitching, it’s hard to provide a complete handicap of this game at this moment, but there’s no reason to try to catch a falling knife with the Tigers in this spot – even if Bibee is winless this year. His advanced metrics suggest he’s not been horrible, but rather unlucky, and this Tigers lineup has been pitiful all season when it comes to scoring runs.

Guardians vs Tigers prediction: Cleveland Guardians ML (-122) at the time of publishing. Playable to -130. 

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