Cleveland Guardians

Cleveland Guardians vs Philadelphia Phillies Prediction, Odds and Picks for Today, 05/23/26

Citizens Bank ParkMLB.TV
Guardians
31-22
Guardians
Today
Phillies
25-26
Phillies
Philadelphia Phillies
Google News

Guardians vs Phillies Pickswise Expert Predictions

Money Line Pick
PHI Phillies Win(-190)

The Guardians extended their winning streak to 7 games yesterday after a 1-0 shutout over the Phillies. Not only was it their 7th win in a row, but it was their 10th in their last 11 and 13th in their last 15. Needless to say, Cleveland is running hot right now. Philadelphia was in a similar boat earlier this week, but the Phillies have now lost 3 in a row after a stretch of 8 wins in 9 games.

Saturday’s pitching matchup pits Cleveland’s Slade Cecconi against Philadelphia’s Zack Wheeler. On the surface, Cecconi’s numbers are awful with a 3-4 record, 5.16 ERA and 1.49 WHIP. At one point, the Guardians were even 0-6 SU in his starts. However, they have won his last 4, while he has surrendered just 4 earned runs across his last 3 starts. Meanwhile, Wheeler is off and running this season after a late start. Through 5 appearances, Wheeler is 3-0 with a 1.99 ERA and a 0.88 WHIP. The Phillies are a perfect 5-0 in his starts. 

Cleveland may be running hot, but the streak figures to ends here. The Guardians are one of the worst teams in the league when it comes to batting average and slugging percentage against righties, and Wheeler is about as elite of a right-hander as it gets. Not to mention, this roster has just 22 combined career at bats against Wheeler outside of Rhys Hoskins, who has 24 from his days playing in the NL. In that small sample size, the team’s batting average against Wheeler is just .217, while its on-base percentage is below .300. Phillies get right on Saturday.

Guardians vs Phillies prediction: Philadelphia Phillies ML (-190) at the time of publishing. Playable to -200. 

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Sam Avellone

Long-time suffering Browns fan born and raised in the greater Cleveland, Ohio area who now resides in SEC country. University of South Carolina alum. Sports handicapper for close to 10 years with a primary focus on NCAAB while enjoying NFL, PGA, NCAAF, NBA, and Soccer. For Sam Avellone media enquiries, please email contact@pickswise.com.
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