Colorado Rockies vs Arizona Diamondbacks Prediction, Odds and Picks for Today, 05/22/26

Game 2 of the series between the Arizona Diamondbacks and Colorado Rockies will be played on Friday night in Arizona. The Diamondbacks have been playing good baseball as of late, and they will be looking for that to continue when they send Michael Soroka to the mound. Soroka, like the Diamondbacks, has been great lately. He has won his last two outings and only allowed three earned runs in his last 18.1 innings pitched. Overall, on the season he has a 3.49 ERA in 49.0 innings. The Rockies will be countering with Tomoyuki Sugano who’s last outing came against the Diamondbacks. The Diamondbacks will be familiar with his stuff and be hoping for a different outcome as the Rockies won that game.

The Rockies are the fifth-worst team in the MLB when it comes to runs allowed. They are averaging 5.3 per game. Their offense is not good enough to keep up with this, as they only average 4.2 runs per game. This is not a recipe for winning baseball games. I think the Diamondbacks will get it done at home. I will be taking them on the run line.

Rockies vs. Diamondbacks prediction: Diamondbacks -1.5 (+105) available at time of publishing. Playable to -105.