Colorado Rockies vs Arizona Diamondbacks Prediction, Odds and Picks for Today, 05/22/26

Game 2 of the series between the Arizona Diamondbacks and Colorado Rockies will be played on Friday night in Arizona. The Diamondbacks have been playing good baseball as of late, and they hope that will continue when they send Michael Soroka to the mound. Soroka, like the Diamondbacks, has been great lately. He has won his last 2 outings and only allowed 3 earned runs in his last 18.1 innings pitched. On the season, he has a 3.49 ERA in 49.0 innings.

The Rockies will counter with Tomoyuki Sugano, whose last outing came against the Diamondbacks. The Diamondbacks will be familiar with his stuff and hoping for a different outcome considering the Rockies won that game.

The Rockies are the 5th-worst team in the MLB when it comes to runs allowed, yielding 5.3 per game. Their offense is not good enough to keep up with this, as they only average 4.2 themselves. This is not a recipe for winning baseball games. I think the Diamondbacks will get it done at home in convincing fashion, so I will take Arizona on the run line.

Rockies vs Diamondbacks prediction: Arizona Diamondbacks -1.5 (+105) available at time of publishing. Playable to -105.

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