New York Mets

New York Mets vs Washington Nationals Prediction, Odds and Picks for Today, 05/21/26

Nationals ParkESPN+
Mets
21-28
Mets
Today
Nationals
25-25
Nationals
Washington Nationals
Google News

Mets vs Nationals Pickswise Expert Predictions

Money Line Pick
WAS Nationals Win(-105)

The New York Mets and Washington Nationals will close out a 4-game series in Washington on Thursday afternoon. The Nationals have won 2 of the first 3 games, including 2 in a row. Furthermore, the Nationals come into this game as the best offensive team in the MLB, averaging 5.6 runs per game. It has been their defense and pitching that has let them down, as they allow the most runs against (5.9).

Washington will send Cade Cavalli to the mound on Thursday, who has been one of their better pitchers this season. He has not allowed more than 3 earned runs in his last 6 starts, and had 8 or more strikeouts in 3 of those games. There are really only 2 bats Cavalli needs to be worried about in the Mets lineup, and they are Bo Bichette and Juan Soto — both of whom have heated up as of late. If Cavalli can neutralize them, I like the Nationals’ chances.

The Mets are a mediocre team, averaging only 4.1 runs per game. With the Nationals being at home and some value on their side, I’m going with Washington in this spot.

Mets vs. Nationals prediction: Washington Nationals ML (-105) available at time of publishing. Playable to -120.

Sign up for Polymarket RIGHT NOW to get instant access and a $50 trading bonus after you make your first $20 deposit! You can join Polymarket by clicking here and trade on our Mets vs Nationals predictions.

Photo of Jon Picks

Jon Picks

NHL handicapper for Pickswise.
Read more about Jon Picks