Toronto Blue Jays vs New York Yankees Prediction, Odds and Picks for Today, 05/21/26

Carlos Rodon has struggled since returning to the Yankees. His first 2 outings since returning from injury have spanned just 8 combined innings while walking 8 batters. He has allowed 5 earned runs with an additional unearned run crossing the plate. While Rodon does have 10 strikeouts and a healthy ground-ball rate, until he finds his form and ability to work deeper into starts, I am not looking to back him monetarily. He faces a Toronto lineup that has been lackluster against left-handed pitching this season. They don’t strike out often, though, and their plate discipline should give them a solid baseline when facing Rodon. We could see several bullpen arms used in this game for New York.

We are likely to see several bullpen arms for Toronto as well, as they are rolling with an opener for this game. Braydon Fisher is set to open Thursday’s game for the Blue Jays, marking his 25th appearance and 2nd time as an opener. Fisher enters play with a 3.08 ERA across 26.1 innings of work; we should only expect an inning or 2 from the right-hander before Toronto mixes and matches.

No matter which arm the opposing pitcher throws with, New York has been a deadly offense this season. Against righties, they rank 7th in wOBA, while they sit 2nd against lefties. Either way, I expect offensive production from New York, and I also look for Toronto to contribute against Rodon’s rust. As a result, I favor the over on the posted game total.

Blue Jays vs Yankees prediction: Over 8 (-115) available at time of publishing. Playable to -120 odds.

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