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Four-pick cross-sport parlay for today 9/10 (+922 odds): MLB, College Football and MLS

Four-pick cross-sport parlay for today 9/10 (+922 odds): MLB, College Football and MLS

Matthew Lowrimore
Matthew LowrimoreAuthor
UpdatedSep 15, 2026
Reading time3 min

We have put together a 4-pick cross-sport parlay that will take you right through Saturday, including picks from the MLB, College Football, and MLS. One pick is taken from each sport with a second pick from College Football. A winning ticket would give us a very nice payout with odds of +922 at DraftKings Sportsbook.

Let’s break down each of these plays.

MLB: Tampa Bay Rays ML (-110) over New York Yankees, 1:05 pm ET

The Rays are projected to put right-hander Corey Kluber on the mound today. Kluber has pitched very well against the Yankees this year, as he’s faced them 4 times, going at least 6.0 innings in every start and only allowing 3 earned runs total. Because Kluber has had so much success against the Yankees, look for the Rays to keep the pressure on the AL East division race.

Be sure to check out our full Tampa Bay Rays vs New York Yankees predictions

College Football: Oklahoma State Cowboys -11.5 (-115) over Arizona State Sun Devils, 7:30 pm ET

The Sun Devils’ defense looked impressive against Northern Arizona, but the Oklahoma State Cowboys’ offense is far more explosive. Senior quarterback Spencer Sanders was sensational last week, recording 6 touchdowns through the air and on the ground. The offense looked unstoppable, producing over 530 total yards. The offense should continue to be dangerous this year and I am not sure if this inexperienced Sun Devils defense can contain them. Oklahoma State is also 5-0 ATS off a straight up win against non-conference opponents. For that reason, backing the Cowboys to cover the spread will be the play.

Be sure to check out our full Arizona State Sun Devils vs Oklahoma State Cowboys predictions

MLS: FC Cincinnati ML (-200) over San Jose Earthquakes, 7:30 pm ET

FC Cincinnati may be struggling at home this year, but San Jose are just awful on the road. They have conceded 32 goals away from home, and with that stat alone it’s not hard to bet against the visitors. Cincinnati should take advantage of playing against a poor road side to keep their playoff position alive. Bet Cincinnati to collect all 3 points in this fixture.

Be sure to check out our full San Jose Earthquakes vs FC Cincinnati predictions

College Football: Georgia Southern Eagles +23.5 (-110) over Nebraska Cornhuskers, 7:30 pm ET

The Nebraska Cornhuskers have been double-digit favorites in both of their games this season, which resulted in an outright loss and a 21-point win where they failed to cover the spread against the North Dakota Fighting Hawks. They are favored by even more this week against a top end Sun Belt team that has plenty of playmakers and the ability to hang with teams of this caliber. The way Nebraska is playing right now, there is no way laying more than 3 scores is worth the risk. For that reason, backing the Georgia Southern Eagles to cover the spread looks to be well worth a play.

Be sure to check out our full Georgia Southern Eagles vs Nebraska Cornhuskers predictions

Pickswise is the home of free sports picks, news and best bets. Check out our expert NFL Picks, NBA Picks, MLB Picks and NHL Picks pages for our latest game picks.

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