NFL Week 10 MNF same game parlay (+845 odds): Los Angeles Rams vs San Francisco 49ers

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Andrew Ortenberg


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I'm an NFL handicapper here at Pickswise who was raised in a household full of sports fanatics. Since I unfortunately never had LeBron James' jumping ability I wasn't able to make it to the NBA, and chose writing about sports as the next best thing. An avid sports bettor myself, I'm excited to get to write about the industry as it gets set to take off across the country. Buckle up. For Andrew Ortenberg media enquiries, please email

The 2021 NFL season has been epic so far. And we’ve got another great game here to wrap up Week 10. The San Francisco 49ers will host the Los Angeles Rams for Monday Night football. An NFC West rivalry showdown. What better way to make this nationally televised game even more exciting than by betting a same game parlay? I just hit one of these on the Falcons/Saints game last week at 13/1, so let’s do it again!

Here we go:

Los Angeles Rams -3.5 (-110)

Darrell Henderson anytime touchdown scorer (-170)

George Kittle anytime touchdown scorer (+170)

Same Game Parlay odds: +845

We have a 3-leg same game parlay which pays out north of 8/1 with FanDuel Sportsbook. Let’s break it down:

Los Angeles Rams -3.5 (-110)

To start this same game parlay off we have the Rams on the spread. Los Angeles took a tough loss against the Titans last week, but that game just felt like a fluke. They had been riding on top of the world, and were due for a letdown. Their defense actually played quite well against Tennessee, Matthew Stafford just had a disaster of a game. He should have a much easier time here against a 49ers defense that just got shredded by Colt McCoy.

San Francisco had no answers for the Cardinals last week, and their defense as a whole has been a big disappointment. They certainly don’t have enough talent in their secondary to keep up with the Rams’ weapons. Los Angeles will add Odell Beckham to the mix here, and it looks like Von Miller is going to make his Rams debut to make their defensive front even scarier.

Be sure to check out our full game preview for Los Angeles Rams vs San Francisco 49ers

Darrell Henderson anytime touchdown scorer (-170)

This correlates nicely with the first leg of our same game parlay. If Henderson is scoring a touchdown, obviously that’s good news for Los Angeles, and the young running back seems quite likely to find the endzone. The Memphis product has scored seven touchdowns in eight games this season. The only times he has failed to score a touchdown have been when the Rams’ offense struggled as a whole. And if the offense struggles as a whole here on Monday night, then they probably aren’t covering the -3.5. James Conner ran all over the 49ers last week and scored three touchdowns, so Henderson should have plenty of success.

George Kittle anytime touchdown scorer (+170)

To wrap this same game parlay up and hopefully bring us home, we’ve got a Kittle touchdown prop. We get a nice odds boost by combining this with the first legs of our same game parlay, when I don’t think it conflicts much. The Rams will be scoring a bunch, but it’s not like the 49ers will get shutout. And if anyone is going to do some damage, it’ll be Kittle. Kittle just returned from an injury last week, and he exploded for 101 yards and a touchdown. He’s the only one Kyle Shanahan seems to fully trust. The Rams have had some trouble covering tight ends, and in his one game against the Rams last year Kittle went off for 109 yards and a touchdown.

What is a Same Game Parlay?

Check out our guide on what is a same game parlay and where can I bet it?

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