The home of our free Week 1 NFL Picks and Predictions. Our expert NFL handicappers research the entire NFL Week 1 schedule, to bring you the best NFL expert picks this week. Check out the entire Week 1 NFL schedule, including the week 1 spreads, betting lines, and money line favorites as well as our picks and predictions. Be sure to head on over to our NFL parlays page to see our week 1 parlay picks and our NFL odds page to ensure you get the best odds on every NFL bet this week.
Spread Pick: Bills -2.5
Spread Pick: Falcons +5.5
Spread Pick: Browns +2.5
Spread Pick: Bears +7
Spread Pick: +6.5
Spread Pick: Lions +4
Spread Pick: Colts -7
Spread Pick: Dolphins -3.5
Spread Pick: Ravens -7
Spread Pick: Jaguars +2.5
Spread Pick: Chiefs -6
Spread Pick: Chargers -3
Spread Pick: Vikings +2
Spread Pick: Giants +5.5
Spread Pick: Cowboys +2.5
Spread Pick: Seahawks +6.5
Thursday, Sept. 8
Buffalo Bills at Los Angeles Rams, 8:20 p.m. (Thursday Night Football)
Sunday, Sept. 11
Kansas City Chiefs at Arizona Cardinals, 4:25 p.m.
Las Vegas Raiders at Los Angeles Chargers, 4:25 p.m.
Green Bay Packers at Minnesota Vikings, 4:25 p.m.
New York Giants at Tennessee Titans, 4:25 p.m.
Tampa Bay Buccaneers at Dallas Cowboys, 8:20 p.m. (Sunday Night Football)
Monday, Sept. 12
Denver Broncos at Seattle Seahawks, 8:15 p.m. (Monday Night Football)
With many different NFL betting sites available, it’s important to shop the odds and lines each game week. Check out the best NFL Week 1 odds from the Top Online Sportsbooks below. You can find all of the NFL week 1 Money line odds, Week 1 NFL Spreads, and Week 1 NFL Total’s.
Check out the NFL Week 1 Spreads and Money Line favorites at all of the best online sportsbooks below.
The defending Super Bowl Champion Los Angeles Rams open the season in what many are billing as a rehearsal for Super Bowl 57. The Bills are the odds on favorite to win Super Bowl 57, led by MVP front-runner Josh Allen. Expect fireworks. The perfect season-opener, perhaps?
A primetime game in a prime time slot. The first Sunday Night Football game of the season sees Tom Brady and the Buccaneers march into Jerry’s World against the Dallas Cowboys. Both teams enter the season with lofty ambitions in a fiercely competitive NFC. An early statement win beckons for the victors.