Below you will find our NFL week 1 picks against the spread and straight up for every game this week. Read our expert’s in-depth NFL week 1 predictions for the best wagers of the opening week of the NFL. Head on over to our NFL parlays page to see our combined picks for week 1 or our NFL odds page to make sure you get the best price on your wager.
The home of our free NFL Picks and Predictions for week 1 of the 2021/22 NFL season.
Our expert NFL handicappers, research the entire NFL Week 1 schedule, leaving no stone unturned to bring you the best NFL expert picks across the week 1 slate.
We take a look through all of the week 1 NFL games, bring you the entire schedule, including the week 1 spreads, betting lines, and Money line favorites and our week 1 NFL picks and predictions will encompass all of these popular NFL Betting lines, alongside our match previews and analysis.
Thursday, Sept. 9
Dallas Cowboys at Tampa Bay Buccaneers, 8:20 p.m. ET (Thursday Night Football)
Sunday, Sept. 12
Philadelphia Eagles at Atlanta Falcons, 1 p.m. ET
Pittsburgh Steelers at Buffalo Bills, 1 p.m. ET
New York Jets at Carolina Panthers, 1 p.m. ET
Minnesota Vikings at Cincinnati Bengals, 1 p.m. ET
San Francisco 49ers at Detroit Lions, 1 p.m. ET
Jacksonville Jaguars at Houston Texans, 1 p.m. ET
Seattle Seahawks at Indianapolis Colts, 1 p.m. ET
Arizona Cardinals at Tennessee Titans, 1 p.m. ET
Los Angeles Chargers at Washington Football Team, 1 p.m. ET
Cleveland Browns at Kansas City Chiefs, 4:25 p.m. ET
Miami Dolphins at New England Patriots, 4:25 p.m. ET
Green Bay Packers at New Orleans Saints, 4:25 p.m. ET
Denver Broncos at New York Giants, 4:25 p.m. ET
Chicago Bears at Los Angeles Rams, 8:20 p.m. ET (Sunday Night Football)
Monday, Sept. 13
Baltimore Ravens at Las Vegas Raiders, 8:15 p.m. ET (Monday Night Football)
Our experts take a complete look at all of the NFL odds for Week 1. The balance between a confident NFL pick and good value odds is an important one, so taking a look at the Week 1 NFL odds is always important ahead of making your NFL Week 1 picks or wagers.
With many different NFL betting lines to focus on in any given match, we take a look at the main three, most popular markets in the NFL week 1 Money line odds, Spreads, and Totals.
Check out all of the best NFL Week 1 odds from the Top Online Sportsbooks below.
Check out the NFL Week 1 Spreads and Money Line favorites at all of the best online sportsbooks below.
Check out all of the NFL Week 1 Totals betting Lines from the top online sportsbooks below.
Where else to start other than the season-opener as the defending champions in Tampa Bay host the Dallas Cowboys. Will plenty of speculation around Dak Prescott’s health, will be see him, will he be 100% and will the Bucs be able to pick up where they left off? plenty of intrigue around this one and a great way to start the season.
The Browns are coming into this season with as much expectation as they have ever had. The Dark horse of many experts and handicappers in the AFC but a tough start against the Chiefs who are looking to make it to three successive Super Bowls. Two stacked teams that we’ll expect to see playing in January, locking horns in week 1. Its so good to have football back.