Pickswise
MLB Thursday three-team mega parlay (+1223 odds): Astros win big

MLB Thursday three-team mega parlay (+1223 odds): Astros win big

Andrew Ortenberg
Andrew OrtenbergAuthor
UpdatedSep 15, 2026
Reading time4 min

We are approaching the home stretch of the 2021 MLB season and we now know more or less where things stand. We don’t have many days of regular season baseball left, why not try to go for a big payday? That’s right; we’re back with another MLB mega parlay, this time a 3-teamer with a payout north of 12/1, and we’re counting on the Astros to pummel the Rangers.

We’re absolutely on fire with these mega parlays. My colleague John Hyslop just cashed the mega parlay on Monday at 11/1 odds, and then I did it on Wednesday at 13/1. Why not make it three days out of four? We’re going big and bold, so let’s not waste any more time. But before we dive in, don’t forget to check out our picks for the side and total on every MLB game, with our team of experts in red-hot form.

Colorado Rockies -1.5 (+250)

Oakland Athletics -1.5 (+125)

Houston Astros -1.5 (-145)

Parlay odds: +1223

Let’s break down each of the legs one by one.

Colorado Rockies -1.5 (+250) over Atlanta Braves

I had Rockies money line in both the Tuesday and Wednesday MLB mega parlays, and they delivered both times. Yet oddsmakers are undervaluing them once again here. Atlanta is just 8-12 in their last 20 games, and I’m not sure why they’re being treated like a top-tier team. The Rockies have won five of six, and will have one of their best pitchers on the mound here in German Marquez.

His last time out, he threw six shutout innings against the Phillies. The Braves will start Ian Anderson, who has only made three starts since returning from a six-week absence. One of those starts was against the Rockies, and he lasted only three innings in that one while giving up nine baserunners, four earned runs, and two home runs.

Be sure to check out our full game preview for Colorado Rockies vs Atlanta Braves

Oakland Athletics -1.5 (+125) over Kansas City Royals

The A’s also came through for us on Wednesday, and we’re also going right back to the well with them. Oakland has been mashing lately, and they’re in the top five in the league in batting average over the last 15 days. They put up 12 runs on Wednesday and now get to face struggling Royals rookie Daniel Lynch. Over his last two starts, Lynch has given up 10 earned runs and four home runs.

Lynch has walked at least three batters in five of his last six outings, and those control issues aren’t going to fly here against a sizzling hot lineup. Oakland will start Paul Blackburn, who is better than he’s being given credit for. Blackburn has made five starts this season. Two of them have been tough, but in the other three he’s given up just five total runs. Two of those three starts were against the Yankees and White Sox, so he’s shown he’s capable of pitching well against offenses much better than this Royals one.

Be sure to check out our full game preview for Oakland Athletics vs Kansas City Royals

Houston Astros -1.5 (-145) over Texas Rangers

To wrap this mega parlay up and hopefully bring us home, we’ve got the Astros. Houston won 7-2 on Wednesday, and they won the first game of this series 15-1. Texas is just playing out the string at this point, and the pitching matchup here is a ridiculous mismatch. The Rangers will start rookie Glenn Otto here for just the fourth start of his career. Texas has lost each of his previous three trips to the hill.

His last time out, Otto gave up eight earned runs to the A’s. He actually pitched decent against Houston in his first start, but the Astros will be licking their chops to get another crack at him. Sending a guy with only 13 innings under his belt to face the lineup with the second-highest OPS in MLB is a tough ask. Houston on the other hand will start Framber Valdez, who has been having a great season. In two starts against the Rangers this year, Valdez has given up only three hits across 13 innings.

Pickswise is the home of free MLB Picks. Check out the latest MLB Prop Bets and MLB Parlays as well as our MLB Best Bets from the experts.

Exclusive Offers
See all
Polymarket — Deposit $10, Get a $50 Trading Bonus
Polymarket
PolymarketDeposit $10, Get a $50 Trading Bonus
$50
Novig — Deposit $10, Get $25 in Trade Credits
Novig
NovigDeposit $10, Get $25 in Trade Credits
$25
Underdog — First-Time Deposit Match + Keep Your $1,000,000
Underdog
UnderdogFirst-Time Deposit Match + Keep Your $1,000,000
$1,000,000
Onyx Odds — Spend $10, Get $111 in Bonus Picks
Onyx Odds
Onyx OddsSpend $10, Get $111 in Bonus Picks
$111
Bet365 — Bet $10, Get $365 in Bonus Bets, Win or Lose
Bet365
Bet365Bet $10, Get $365 in Bonus Bets, Win or Lose
$365
Fanatics — Bet $20, Get $350 in FanCash
Fanatics
FanaticsBet $20, Get $350 in FanCash
$350
BetMGM — Get Up to $1500 in Bonus Bets if your First Bet Does Not Win
BetMGM
BetMGMGet Up to $1500 in Bonus Bets if your First Bet Does Not Win
$1,500
ProphetX — Trade $50, Get $75
ProphetX
ProphetXTrade $50, Get $75
$75
Rebet — Get a 100% Deposit Match up to $100
Rebet
RebetGet a 100% Deposit Match up to $100
$100
FanDuel — Bet $5, Get $350 in Bet Reset Tokens over 7 Days
FanDuel
FanDuelBet $5, Get $350 in Bet Reset Tokens over 7 Days
$350
When you click our links to visit an operator and sign up, we may receive a commission at no extra cost to you. This financial relationship helps support our site.
Pickswise
Get exclusive 
free sports picks
to your email
subscriber 1
subscriber 2
subscriber 3
18K users have
already subscribed
Enter your email address
By signing up you agree to our terms and privacy