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NFL Monday Night Football Jacksonville Jaguars vs Buffalo Bills Same Game Parlay -- Travis Etienne keeps the Jags alive at +634 odds

NFL Monday Night Football Jacksonville Jaguars vs Buffalo Bills Same Game Parlay -- Travis Etienne keeps the Jags alive at +634 odds

Ricky Dimon
Ricky DimonAuthor
UpdatedSep 15, 2026
Reading time3 min

Why have only 1 Monday Night Football game when you can have 2? As the NFL Week 3 schedule indicates, the answer to that question is that there is no reason to have only 1! The pleasure and fun will be doubled on Monday when the Jacksonville Jaguars pay a visit to the Buffalo Bills and the Cincinnati Bengals entertain the Washington Commanders. It’s already desperation time for Jacksonville in the former contest, as Trevor Lawrence and company are winless through 2 weeks. Let’s get into our Jaguars vs Bills Same Game Parlay picks at +634 odds, with the matchup getting underway at 7:30 pm ET on ESPN. Also, be sure to check out our NFL picks for both Jaguars vs Bills and Commanders vs Bengals.

Jaguars +3.5 alternate spread (+116)

Travis Etienne to record 70+ rushing yards (+220) 

Josh Allen Over 228.5 passing yards (-110) 

Jaguars vs Bills Same Game Parlay odds: +634

Part of the value in a Same Game Parlay, of course, is that all of its components can be correlated if you so choose. That is some of the plan here, as Jacksonville running back Travis Etienne racking up his fair share of rushing yards would obviously work well with a Jaguars cover. At the same time, plays that aren’t correlated drive up the overall payout of the parlay. That is the case with backing Buffalo quarterback Josh Allen to have a decent night through the air. But even if he does, there is no reason why the visitors can’t keep it close. Let’s break down each of the 3 legs.

Jacksonville Jaguars +3.5 alternate spread over Buffalo Bills (+116)

Despite hosting a winless opponent, this is not an easy spot for Buffalo. Jacksonville is almost certainly better than its 0-2 record suggests. The Jags lost to the Miami Dolphins and Cleveland Browns by a combined 8 points and were quite frankly snakebit by some bad luck in each of those 2 setbacks. Jacksonville’s defense has been stellar, while Lawrence and the offense should be able to improve at the expense of a Buffalo defense that is already dealing with injuries in the secondary and at linebacker. It is true that the Bills have been pretty good so far, but they just barely scraped past the Arizona Cardinals and their blowout of Miami had more to do with the Dolphins’ mistakes. I think Jacksonville can keep this within a field goal.

Read our full Jacksonville Jaguars vs Buffalo Bills predictions

Travis Etienne to record 70+ rushing yards (+220) 

Etienne has gotten 25 carries through 2 contests, more than twice as many as Tank Bigsby. The former Clemson standout is clearly RB1 in Jacksonville, and a lot of opportunities should result in plenty of yards against Buffalo. Through 2 outings, the Bills are allowing an average of 131.5 rushing yards on 4.5 yards per carry. In last year’s 25-20 victory over this same Bills squad, Etienne erupted for 136 yards and 2 touchdowns on 26 attempts. Asking him to reach the 70 mark on Monday night definitely shouldn’t be too much.

Get Prop Holliday’s best Jaguars vs Bills player prop bet for tonight

Josh Allen Over 228.5 passing yards (-110)

In the Bills’ loss to the Jaguars last October, Allen completed 27 of 40 passes for 359 yards. Admittedly, wide receiver Stefon Diggs is gone – therefore Allen does not have quite as many weapons at his disposal. However, 228.5 is not a large total for someone of his caliber. Count on the star QB having another productive day at the office against Jacksonville.

We have a pair of Jaguars vs Bills touchdown scorer best bets at +115 odds

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