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Sunday cross-sport parlay: 4-team multi-sport parlay at +1355 odds, including today's MLS and NFL Week 6 picks and predictions

Sunday cross-sport parlay: 4-team multi-sport parlay at +1355 odds, including today's MLS and NFL Week 6 picks and predictions

Matthew Lowrimore
Matthew LowrimoreAuthor
UpdatedSep 15, 2026
Reading time3 min

We have put together a 4-pick cross-sport parlay that will take you right through Sunday, including picks from the NFL and MLS. Three picks are taken from the NFL with one from the MLS. A winning ticket would give us a very nice payout with odds of +1355 at DraftKings Sportsbook.

NFL pick today: Atlanta Falcons +4 over San Francisco 49ers (-105), 1:00 pm ET

San Francisco could be tired and shorthanded against a Falcons team that’s a lot better than most realize. Atlanta is 2-3 and could easily be a lot better. They blew a 15-point fourth-quarter lead in Week 1, and had chances to beat the Rams and Bucs late on the road in their other losses. The Falcons are the only team in the league who have been perfect against the spread, therefore backing the Falcons to cover looks to be worth a play.

Be sure to check out our full San Francisco 49ers vs Atlanta Falcons predictions

NFL pick today: Cincinnati Bengals -3.5 over New Orleans Saints (+100), 1:00 pm ET

The Saints are coming off a nice win against the Seahawks but face a much tougher task against the Bengals defense. Their biggest weapon last week was Taysom Hill, who rushed for 112 yards and 3 touchdowns, but the Seattle defense ranks 24th against the run and is allowing over 170 rushing yards per game, which is the highest in the NFL. The Bengals are not only allowing fewer than 100 rushing yards per game this season, but they have given up only 1 rushing touchdown.

Add Joe Mixon into the mix against a run defense that is allowing 130 rushing yards per game with 4 rushing touchdowns and the firepower for Cincinnati may be too much to handle.

Be sure to check out our full Cincinnati Bengals vs New Orleans Saints predictions

NFL pick today: New York Giants +5.5 over Baltimore Ravens (-105), 1:00 pm ET

Oddsmakers have installed the G-Men as significant home underdogs against the Baltimore Ravens. However, it’s hard giving Baltimore much credit for sneaking past a struggling Bengals team by 2 points at home last week.

New York has all the momentum in the world, and they aren’t likely to be embarrassed at home. Last week they were able to hold Aaron Rodgers to 5.7 yards per attempt, so the defense should at least be able to do enough to keep this one close.

Be sure to check out our full New York Giants vs Baltimore Ravens predictions

MLS pick today: Austin FC ML over Real Salt Lake (-110), 3:00 pm ET

Austin FC cooled off as the campaign progressed after sitting comfortably in 2nd place all year. At home they have proved to be a tough out for the visiting sides, going 8-3-6 while racking up 42 goals.
Real Salt Lake could be in a bit of trouble in this fixture due to their play on the road. They are in the middle of the pack in MLS when it comes to away form with 15 points in 17 games, but they have allowed an average of 1.76 goals per game. This is a spot where we should see the home team win, therefore backing Austin to win and advance to the next round will be the play.

Be sure to check out our full Real Salt Lake vs Austin FC predictions

Pickswise is the home of free sports picks, news and best bets. Check out our expert NFL Picks, NBA Picks, MLB Picks and NHL Picks pages for our latest game picks.

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