Panthers vs Packers Predictions, Picks, Odds & Betting Guide
We've reached Week 8 of the 2026 NFL season and things get started with Thursday Night Football at Lambeau Field as the Carolina Panthers battle the Green Bay Packers. Carolina currently sits atop the NFC South, but just got decimated by the Buccaneers. As for the Packers, they just got beaten by the Lions and despite being 4-3 are last in the NFC North. Can Carolina retain its division lead, or will Green Bay propel itself off the bottom?
Panthers vs Packers kicks off at 8:15 PM ET live on Amazon Prime Video, and we've got all betting bases covered. You can lock in our expert NFL picks on the side and total from pro NFL bettor Chris Farley, who is on an 8-2 run with his 5-star best bets! Meanwhile, Bobby Stanley has his best Panthers vs Packers player prop bets, including plays at +185 and +300 odds, while JutPicks has his Panthers vs Packers anytime touchdown scorer predictions and is looking to build on primetime winners at +400, +330, +280 and +250 odds! You can also get Ricky Dimon's Panthers vs Packers Same Game Parlay at +850 odds. Let’s break it all down.
Panthers vs Packers Latest Odds
Odds courtesy of bet365 and available at 8:30 AM ET on Thursday, October 29. Find out the latest NFL odds for every Week 8 matchup.
Money Line: Panthers (+165) vs Packers (-200)
Point Spread: Panthers +3.5 (-108) vs Packers -3.5 (-112)
Game Totals: Over 47.5 (-103), Under 47.5 (-117)
Panthers vs Packers Predictions & Picks
Chris Farley’s Panthers vs Packers Spread Pick: Packers -3.5 (-110)
Carolina is coming off a blowout loss to a previously 1-5 Tampa Bay team. Green Bay is 3-1 in its last four games and playing in the friendly confines of Lambeau Field. The Packers should be able to get a comfortable win in this one.
Chris Farley’s Panthers vs Packers Total Prediction: Over 47.5 (-103)
Offenses that have had a pulse have had no issue scoring on the Panthers. In Week 1, for example, the Bears sprinted to 59 points. On the other side of the ball, Bryce Young and company should be able to produce against the Packers.
Get the full analysis for pro NFL bettor Chris Farley's 5-star Panthers vs Packers predictions for TNF - he's on an 8-2 run with his best bets!
Panthers vs Packers Player Prop Bets
Best Panthers vs Packers Player Prop Bet: Christian Watson (GB) 60+ Receiving Yards + Anytime TD Scorer (+185)
Matthew Golden was held out of practice this week with shoulder and foot injuries. It's a short week and I expect the Packers to lean on Watson heavily as a result. The Panthers' defense is big on closing the middle of the field and gives the third-most Cover 3 looks in the league. That should only continue with starting CBs missing for this one. I brought this line down to the median of 64 (60 in this case), and I like Watson to deliver an explosive TD on TNF.
Don't miss out on Bobby Stanley's best Panthers vs Packers player prop bets for tonight, featuring another play at +300!
Panthers vs Packers TD Scorer Best Bet: Bryce Young (CAR) Anytime Touchdown Scorer (+750)
We're taking a shot in the dark here with Bryce Young scoring a touchdown with his legs, as his designed runs are down and he's throwing the ball down the field much more efficiently than last season. That said, seven skill players, including Chuba Hubbard, Jalen Coker and Tetairoa McMillian, are priced at lower than +200 odds. I don't feel comfortable laying those prices on a short week, so here's to throwing a dart on Young running in a touchdown.
Find out Justin Martin's other Panthers vs Packers TD scorer best bet for TNF at +340 odds! Can he add to primetime winners at +400, +330, +300, +290, +280 and +220 this season?
Carolina Panthers vs Green Bay Packers Same Game Parlay
Packers -3.5 over Panthers (-112)
Carolina got humiliated 43-13 at home last week by a previously 1-5 Bucs team in a game that was 33-6 by halftime. Bryce Young and company now have to face a Green Bay defense that ranks top 10 league-wide against the pass, top 10 in yards per pass attempt allowed and #1 with nine interceptions. On the other side of the ball, the Panthers are giving up the sixth-most points in the NFL at 27.7 per game. The Packers lost to the Lions last Sunday, but that was a three-point margin on the road against a very good team that was coming off a bye week.
Josh Jacobs (GB) Over 58.5 Rushing Yards (-111)
The Panthers quite simply have the worst run defense in the NFL. They are dead last in rushing yards allowed (153.2 per game) and yards per carry allowed (5.2). Jacobs missed the first six weeks of the 2026 campaign due to suspension, but he has a game under his belt now and should only be getting better and better. The Alabama product amassed 91 yards from scrimmage and a touchdown against the Lions, so the bar is already pretty high.
MarShawn Lloyd (GB) to Score a Touchdown (+310)
I’m going all in on the Packers’ ground game – which, admittedly, is not something you normally want to do. However, the Panthers’ run defense is just that bad. Moreover, a positive game script – which we need for the first leg of this parlay to cash – calls for Green Bay to build a lead and then work the clock by keeping the ball on the ground. When the home side hits the red zone, there is no reason why Lloyd can’t get involved. He has scored three touchdowns in the last three games, including one last week even after Jacobs was back from his absence.
Panthers vs Packers SGP odds: +850
After recent SGP winners at +750, +700 and +650, don't miss Ricky Dimon's full analysis for his Panthers vs Packers Same Game Parlay for TNF
NFL Week 8 Picks
Check out our expert NFL predictions for the Week 8 matchups below:
