2025 NFL Draft Betting Guide: Expert NFL Draft Predictions, Picks & Best Bets
Ladies and gentlemen, welcome to the 2025 NFL Draft! One of the most exciting weeks in the football calendar is upon us, and while the #1 pick is almost a lock at this point (Cam Ward to the Titans is currently -10000), there’s sure to be a ton of chaos that follows with plenty of superstars waiting in the wings and lots of teams rumored to be signing Colorado QB Shedeur Sanders. We also have a stacked group of offensive linemen and cornerbacks in the mix. On top of that, rumors have been rampant around teams trading up, so it’s sure to be a memorable night. Our NFL experts have scoured the odds boards and have picked out their best bets, and even created a full first-round NFL mock draft! Let’s dive in.
2025 NFL Draft best bets and predictions
- Lock in our NFL Draft position best bets on when players will be selected, including 2 predictions at plus-money odds!
- Our expert’s NFL Draft order picks for the first three selections in the 2025 draft, including one surprise play at +550!
Pickswise’s 2025 NFL mock draft
- Don’t miss our expert’s 2025 NFL mock draft, featuring picks for the ENTIRE first round to help with your betting picks on Thursday night!
