Miami Dolphins vs San Francisco 49ers NFL predictions, odds, spreads & betting lines: It's Tua time

Miami Dolphins quarterback Tua Tagovailoa (1) celebrates after defeating the Baltimore Ravens at Hard Rock Stadium
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Ricky Dimon


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Since graduating from Davidson (The College That Stephen Curry Built), I have been writing about sports -- just about any and all you can think of! -- and coaching tennis in Atlanta, GA. Beyond the four major sports, I am an avid tennis fan and cover the ATP Tour on a daily basis. If I'm not busy writing, you can generally find me on a tennis court or traveling the world wherever a sporting event takes me. For Ricky Dimon media enquiries, please email
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The Miami Dolphins visiting the San Francisco 49ers is quite simply one of the best matchups of Week 13 in this NFL season. There are plenty of interesting storylines surrounding this game, including the fact that Dolphins head coach Mike McDaniel is a former protégé of 49ers head coach Kyle Shanahan. More importantly, both teams are good. Miami is 8-3 and only a half-game back of Buffalo in the AFC East, while San Francisco is 7-4 and atop the NFC West.

Here are our predictions and best bets for this Dolphins-49ers showdown.

Be sure not to miss any of our NFL picks for Week 13!

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Miami Dolphins vs San Francisco 49ers spread, odds & betting lines

Point Spread: Dolphins +4, 49ers -4
Total Points Over/Under:
46.5 points
Money Line Odds: Dolphins +175, 49ers -205

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Miami Dolphins vs San Francisco 49ers expert picks

We have 2 NFL picks for this week’s clash between Miami and San Francisco. Let’s take a look.

Against the spread pick: Dolphins +4 (-110) over 49ers

It will be fascinating to see which side the familiarity between McDaniel and Shanahan ends up benefiting more. The thinking here is that it will be Miami. The Dolphins have put up at least 30 points 4 consecutive contests and have won 5 in a row overall. Tua Tagovailoa would be in the MVP discussion if not for Patrick Mahomes. San Francisco is being hyped up as the possible best team in the NFC and a Super Bowl contender, but all of that talent hasn’t translated into much domination on the field. Last week in the 49ers’ win over the Saints they looked uninspiring for the most part and they haven’t been able to execute in the red zone all season long. The last time these Niners faced an opponent that is actually playing well they lost by 21 points to the aforementioned Mahomes’ Kansas City squad. When you can get 4 points with a team as good as Miami, it’s an opportunity that should be taken.

Be sure to check out our full Miami Dolphins vs San Francisco 49ers predictions

Over/Under totals pick: Under 46.5 (-110)

Familiarity between coaching staffs often results in lower-scoring affairs and more conservative offense. McDaniel and Shanahan will probably spend most of the first half of this contest feeling each other out. People might think that the 49ers’ recent resurgence has been driven by their offense since it is talked about so much following the acquisition of Christian McCaffrey. However, the opposite is true. San Francisco’s defense has been paving the way to success. Speaking of McCaffrey, he is banged up (what’s new) and Elijah Mitchell is back on injured reserve with another injury. Fortunately for the Niners, their defense is a lot better than the ones the Dolphins have been facing in recent weeks. Look for this to be somewhat of a defensive battle.

Be sure to check out all of our expert betting insight, analysis and even more NFL Predictions and Best Bets from the rest of the Week 13 action.

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