NCAAF

LSU vs Ole Miss Same Game Parlay: Picks & Predictions

UpdatedSep 18, 2026

Reading time4 min

The Game of the Week in college football will kick off at 7:30 PM ET in Oxford, Mississippi, when the Ole Miss Rebels will look to exact some revenge against Lane Kiffin and the LSU Tigers at Vaught Hemingway Stadium. This outstanding SEC matchup will be broadcast on ABC, with all eyes on the likes of Trinidad Chambliss, Kewan Lacey, Sam Leavitt and, of course, Kiffin himself.

To get you set for this massive showdown on Saturday, I’ve put together an LSU vs Ole Miss Same Game Parlay with +850 odds, courtesy of DraftKings Sportsbook. Let’s get right into it, and don’t forget to check our college football picks throughout the week for picks and predictions on every FBS contest.

Ole Miss ML (+130)

Over 57.5 (-108)

Trey'Dez Green TD (+155)

LSU vs Ole Miss Same Game Parlay Odds: +850

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LSU vs Ole Miss Same Game Parlay Pick: Ole Miss Rebels ML over LSU Tigers (+130)

The emotions around this game make it a hard one to handicap on paper. However, I can only look toward Ole Miss now that the Rebels are catching a full three points at home. This line is just a bit inflated, especially since you have to juice up the home field advantage by a couple of points in this spot. I understand that LSU has looked extremely impressive to this point, but it's important to remember that the Tigers dominant win over Clemson is already aging poorly and Ole Miss has the more impressive victory between these teams. Not only am I getting the better quarterback with Chambliss in this game, but if Leavitt is unable to run/scramble as much due to an undisclosed injury, that obviously gives the Rebels defense an important leg up on the LSU offense. All things considered, I'll ride with the home 'dog to win outright.

Get our full LSU vs Ole Miss prediction for CFB stats, trends and more on tonight's game

LSU vs Ole Miss Parlay Pick: Over 57.5 (-108)

Regardless of which team comes out on top on Saturday, we should see a tremendous display of offense. These teams are very familiar with each other, and the same goes for the coaching staffs on both sides. LSU was probably hiding a few things on tape against Louisiana Tech last week, and the same goes for Ole Miss in a sleepy spot against lowly Charlotte. Look for Chambliss to be unleashed with his legs to keep this feisty Tigers defense off balance, while LSU should have no trouble attacking this vulnerable Ole Miss secondary when it has the ball. It wouldn't shock me if both teams reached 30 points in this one, so let's roll with the over.

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LSU vs Ole Miss SGP Pick: Trey'Dez Green (LSU) Anytime Touchdown Scorer (+155)

To close out our Same Game Parlay, I'll back Trey'Dez Green to find the end zone for the second time this season. The LSU tight end is easily one of the best at his position in the nation, and he should be in a position to succeed on Saturday against an Ole Miss defense that was shredded by Louisville's passing offense in the second half of their Week 1 contest. Green has quickly proven himself to be a viable target for Leavitt, racking up 10 receptions for a combined 162 yards over his first two games this season. We'll be seeing plenty more from Green this season, and I'll gladly take the best price in market for him to tally another touchdown in the Magnolia Bowl.

Keep an eye on our college football best bets for our top plays for Week 3!