NFL betting guide: Expert 2022 Week 3 NFL picks, predictions, odds & best bets

Tampa Bay Buccaneers quarterback Tom Brady (12) reacts against the Dallas Cowboys at AT&T Stadium.
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Phil Agius


Show Bio

I've been writing about the NFL and a host of other sports for the UK's top daily betting paper the Racing Post for more than 20 years. An incurable Browns fan (1-31 survivor), I also specialise in all kinds of motorsport betting including F1, MotoGP, IndyCar and NASCAR. For Phil Agius media enquiries, please email

Welcome to the Pickswise NFL Week 3 betting guide. The first two weeks of the 2022 NFL season have produced some unbelievable games, and Week 3 is already underway after the Browns moved to 2-1 by beating the Steelers 29-17 on Thursday Night Football.

Week 3 will no doubt produce more great entertainment with Bills vs Dolphins and Packers vs Buccaneers among the games that stand out on Sunday’s slate.

Our experts have done the hard work so you have everything you need to bet better and get the right results. This is your one-stop shop for everything you need to make the most of your NFL Sunday — and Monday night’s game too!

Don’t forget to check out our great new game previews, which now include prop picks, projections, trends and same game parlays!

Our handicappers have made a fantastic start to the 2022 season and our 3-star Best Bets are 7-2 on the year.

NFL Week 3 picks

  • NFL picks against the spread and total for EVERY Week 3 game
  • NFL best bets – we have a 7-2 record on our 3-star plays this season and EIGHT picks this week!
  • NFL parlays

NFL Week 3 expert betting picks and predictions

NFL Week 3 prop bets

NFL Week 3 Promo Codes

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Find all the latest Sportsbook Promo Codes and Bonuses for NFL Week 3, including sportsbooks live in your state.

NFL Week 3 big-game predictions

Watch Pickswise Playbook!

Our weekly NFL show Pickswise Playbook, presented by Superbook Sports, is hosted by Lauren Jbara and Jared Smith and features former NFL player Tank Williams as this week’s guest.

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