Caleb Wilfinger
Show Bio
Welcome to the Pickswise NFL Week 6 betting guide. The 2022 NFL season has reached this point with just the 5-0 Philadelphia Eagles remaining unbeaten while every team has at least 1 victory. Week 6 got off to a slow start, with the Commanders beating the Bears 12-7 on Thursday Night Football. Things can only get better after that, and if the previous Sunday slates this season are anything to go by we will be in for a real treat again.
This week’s slate features one of the biggest games of the season, as the Buffalo Bills will take on the Kansas City Chiefs at Arrowhead Stadium. We’ll also have an NFC East showdown between the Cowboys and Eagles, plus Ravens vs Giants, Vikings vs Dolphins, Colts vs Jaguars, Bengals vs Saints and more!
Our experts have done the hard work so you have everything you need to bet better and get the right results. This is your one-stop shop for everything you need to make the most of your NFL Sunday — and Monday night’s Broncos vs Chargers game. Don’t forget to check out our great new game previews, which now include prop picks, projections, trends and Same Game Parlays.
Our handicappers have made a fantastic start to the 2022 season, as we’re 19-8 on our best bets this season! Be sure to also check out our EXCLUSIVE TD scorer odds boost for Week 6 from DraftKings Sportsbook.
NFL Week 6 picks
- NFL picks against the spread and total for EVERY Week 6 game
- NFL best bets – we have an 19-8 record on our 3-star plays this season
- NFL parlays
NFL Week 6 expert betting picks and predictions
- Jared Smith’s Week 6 best bets
- NFL Week 6 mega parlay (+962 odds!)
- The Dog House: NFL best underdog bets
- Our NFL experts’ best bets
- Millionaire maker 12-team parlay
- Clevta’s best bet for Broncos vs Chargers on Monday Night Football
NFL Week 6 prop bets
- Week 6 anytime touchdown scorer picks featuring our EXCLUSIVE DraftKings odds boost
- Sunday 1:00 pm game player props
- Sunday 4.25 pm game player props
NFL Week 6 Promo Codes
- BetMGM: Bet $10 Win $200 if either NFL Team scores a TD, Claim HERE
- DraftKings: Bet $5+ On Any NFL Pre-Game ML, Get $200 If Your Bet Wins, Claim HERE
- FanDuel: Bet $5 Get $150 in Free Bets + 3 months of NBA League Pass, Claim HERE
- Caesars: Up To $1,250 Back On Your First Bet + 1000 Tier Credits + 1000 Reward Credits®, Claim HERE
- PointsBet: Get 4x $200 Second-Chance Bets For The NFL, Claim HERE
Find all the latest Sportsbook Promo Codes and Bonuses for NFL Week 5, including sportsbooks live in your state.
NFL Week 6 big-game predictions
- Buffalo Bills vs Kansas City Chiefs
- Baltimore Ravens vs New York Giants
- New York Jets vs Green Bay Packers
- Minnesota Vikings vs Miami Dolphins
- Cincinnati Bengals vs New Orleans Saints
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Pickswise is the home of free NFL Picks and NFL Odds. Check out the latest NFL Prop Bets and NFL Parlays as well as expert NFL Underdog Picks and NFL Computer Picks.
