NFL betting guide: Expert 2022 Week 12 NFL picks, predictions, odds & best bets

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Caleb Wilfinger

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Deputy Editor for Pickswise with years of experience handicapping and giving out winning picks. Lover of all US sports and Southampton FC. For Caleb Wilfinger media enquiries, please email contact@pickswise.com.
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Welcome to the Pickswise NFL Week 12 betting guide! This week’s action got underway with a trio of Thanksgiving Day games, but there’s still plenty in store for Sunday’s slate.

The early afternoon slate has a couple interesting matchups in store, with the Cincinnati Bengals and the Tennessee Titans being the main attraction. The later slate sees the San Francisco 49ers hosting the New Orleans Saints, the Arizona Cardinals hosting the banged-up Los Angels Chargers and the Kansas City Chiefs hosting a depleted Los Angeles Rams team. All of that paves the way for a Sunday Night Football matchup that sees the Green Bay Packers take on the NFC-leading Philadelphia Eagles.

Our experts have done the hard work so you have everything you need to bet better and get the right results. This is your one-stop shop for everything you need to make the most of your NFL Sunday — and for Monday night’s Pittsburgh Steelers vs Indianapolis Colts game. Don’t forget to check out all our NFL predictions for Week 12.

NFL Week 12 picks

NFL Week 12 expert betting picks and predictions

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Find all the latest Sportsbook Promo Codes and Bonuses for NFL Week 12, including sportsbooks live in your state.

NFL Week 12 big-game predictions

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