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NFL Predictions Today

NFL predictions today, for every game of the 2026-27 season. Our expert NFL predictions come with detailed research, statistical analysis and the key trends you need to know. That's why we were up +82.1 units, with 158 winning ATS predictions and 151 winning totals predictions in the 2025-26 season, including the playoffs.

If you're looking for Pickswise NFL predictions, then you've come to the right place. Pickswise has been America's #1 destination for NFL predictions for nearly a decade now, and our success speaks for itself. In the 2025 season, the NFL predictions Pickswise put out delivered a winning record of 311-251-4 for a profit of +90.1 units!

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Free NFL Predictions

Pickswise NFL predictions are determined by our red-hot team of handicappers, who have years of experience to give you the most accurate NFL score predictions in the business. Every pick comes with a guarantee of hours of research from experts who know how to navigate the best bets from major sportsbooks.

And that's proven in the results. After all, if you're looking for NFL predictions today, you want to make sure you're getting it from a source that you can trust. While we don't pledge to win all the time, we do promise that we'll give you in-depth analysis and meaningful stats and trends to ensure you're more informed about the game than before you arrived.

But make no mistake, when it comes to our NFL game predictions today, we do tend to win. As mentioned, we finished last season 90.1 units in profit, and although 2024 saw a down year as we lost -31.3 units, in 2023 we delivered a winning record of 305-256-8 for +65.3 units. The 2022 NFL season saw us finish up +4.9 units. So with a profit of +129 units across the last four seasons, you can trust Pickswise NFL predictions.

Being profitable for any bettor is hard enough, but when you have to do it while navigating a massive 18-week, 272-game regular season with every matchup covered, it can feel nearly impossible. But with our NFL predictions Pickswise has a team of seasoned NFL analysts that have proven their ability and then some. For the 2026-27 NFL season, you can rest assured that our NFL score predictions today will look to continue that tremendous success.

NFL Predictions This Week

If you're looking for NFL predictions this week, then you've come to the right place. Here at Pickswise, we provide football predictions this week, next week and every week for every game of the season. Our expert team of analysts break down the entire slate with their NFL predictions for this week, covering all the matchups on the docket with unbeatable data and insight.

We always have our fingers on the pulse, too. If there's a big-name injury or an unlikely team building momentum, our experts know about it and will make sure you know too. NFL spread betting is one of the most volatile forms of wagering in the game, and we know how key the number is when handicapping for our NFL predictions this week. We keep an eye on any betting line shifts, and will tailor our analysis accordingly.

NFL Playoff Predictions

Contrary to what the title implies, Pickswise handicappers don't believe in only giving NFL playoff predictions before the start of the season and at the start of playoffs - NFL playoff predictions can come at any time.

We’ll give some NFL futures predictions on which teams we expect to make or miss the NFL playoffs, and we've had some success in that department in recent years. In 2024, we correctly predicted the Washington Commanders would make the NFL playoffs at +310 odds, and they ended up making it all the way to the NFC Championship game! Our expert handicappers followed that up with NFL playoff predictions on the Jacksonville Jaguars at +180 and Chicago Bears at +184 to reach the postseason, and both obliged.

Sportsbooks allow bettors to wager on teams to make or miss the postseason at any time, and that ability extends to us. So with that in mind, we may give out NFL playoff predictions during the regular season, if we see value on a team running the table and reaching the playoffs, or if a team has made a hot start but could run out of steam.

We'll of course also deliver NFL Playoffs predictions for the start of the postseason on every game Super Wild Card Weekend, the Divisional Round, the Conference Championships and, of course, Super Bowl 61. In addition, you can also get our expert NFL Playoff bracket predictions to help you win your office pool.

Understanding NFL Predictions

An NFL prediction from our experts takes tons of different elements into consideration. From team statistics and metrics to player injuries, weather conditions and historical trends and head-to-heads, we determine the most likely outcome and score of the matchup for our Sunday football predictions. We then take that score prediction and apply it to the spread and total available at the sportsbook. If we're predicting a team to win by seven points and the sportsbook projects them to win by four, we've just found ourselves a prime American football prediction.

We run this process for every game, so whether you're looking for standard Sunday football predictions or MNF and TNF primetime predictions, our analysts will have you covered with their insights to help you know who holds the edge before kickoff.

Why Trust Pickswise NFL Predictions?

If your whole analysis is just a“gut feeling” and you don't have any stats or analysis to back it up, it's just a guess. We don't believe in guessing when it comes to Pickswise NFL predictions. Instead, our expert handicappers utilize a number of different strategies and approaches that have proven to be winners over the years, sharing their wealth of experience and knowledge to help you bet better. From tapping into key algorithms and statistical models to tracking player metrics and injury reports, every NFL prediction is backed up by hours of research.

Here are just a few reasons why you an trust the Pickswise NFL predictions:

  • Winning results - our experts have had winning NFL seasons in three of the past four years, delivering overall profit of 129 units
  • Experience - all of our handicappers have been betting on NFL for years. They know how to formulate winning strategies, and are now passing those insights on to you
  • Transparency - if we win we'll shout about it, but we don't hide from our losses either. We can't guarantee that every pick will be a winner, but we can guarantee our very best effort to five you the best information available
  • Community - Pickswise wouldn't exist without you and your support. We're here to deliver great NFL predictions for every game of the season to deliver a positive experience for every single user

How Pickswise Makes NFL Predictions

Ever wondered how the Pickswise experts make their NFL predictions? Here's your chance to get the lowdown, as we pull back the curtain and reveal our handicapping process.

For starters, we utilize algorithms and data models to simulate the game thousands of times and give a predicted score. However, this is just the starting point. That is followed up by the implementation of our power ratings, which are updated every week for all 32 teams. Through these power ratings, we are able to establish what the spread and total would be for each matchup.

From there, team and player metrics are analyzed, looking for strengths and weak spots in each team, while player news and the injury report is also factored in. Weather can of course also play a part, even if the matchup is taking place inside a dome, as some teams and players are much better in enclosed conditions than outside.

All of these elements are combined to determine who will win and lose, and what the margin of victory is likely to be. This is crucial, as even if a team is expected to win, if that NFL prediction is only by four points and the sportsbooks have the spread available at +7, then the underdog would be the team to bet on in this instance, even if we don't believe that they'll win.

The golden rule in NFL betting is to always factor in the number above all else, not just who you think will win.

This is the Pickswise NFL predictions method, and it's a strategy that has performed well for us over the years.

NFL Draft Predictions in 2026

The NFL Draft is one of the biggest events in the NFL calendar, as it takes place every year in the final few days of April. While the 2026 NFL Draft has already taken place, our NFL Draft predictions can drop at any time as we're already looking ahead to the 2027 edition.

For those new to the sport, the NFL Draft is where college football players are selected to join NFL teams as they turn professional. The order of the 2027 NFL Draft will be determined by team record, as whoever does the worst gets the #1 pick, the second-worst team gets the #2 pick, etc.

While the showpiece event won't take place until 2027, you can still make NFL Draft predictions in 2026, as the sportsbooks already have odds available for a number of markets, including who will be the #1 overall pick.

To be successful with NFL Draft predictions, you need to have a good understanding of both the NFL and college football. In college football, you need to know the players to gauge who will likely be the first player off the board. But on top of that, you also need to make an NFL Draft predictions order, as the player you expect to be selected first also needs to be a hole that the #1 team needs to fill. For example, if Patrick Mahomes gets injured and the Kansas City Chiefs end up picking #1 overall, it's highly unlikely they'll select a quarterback, although they could trade the pick away.

NFL Draft predictions take a lot of research, analysis and skill, and here at Pickswise, we'll look to keep you as informed as possible in the run up to April 2027.

Key Dates and Matchups for the 2026-27 NFL Season

To make sure you're all set for the 2026 NFL season, we've put together an extensive list of all the standout games and dates, all of which you'll be able to get our Pickswise NFL predictions for!

  • Wednesday, September 9, 2026: 107th NFL Season Kickoff Game - New England Patriots vs Seattle Seahawks
  • Thursday, September 10, 2026: NFL International Game in Melbourne, Australia - San Francisco 49ers vs LA Rams
  • Sunday, September 27, 2026: NFL International Game in Rio de Janeiro, Brazil - Baltimore Ravens vs Dallas Cowboys
  • Sunday, October 4, 2026: NFL International Game in London, England - Indianapolis Colts vs Washington Commanders
  • Sunday, October 11, 2026: NFL International Game in London, England - Philadelphia Eagles vs Jacksonville Jaguars
  • Sunday, October 18, 2026: NFL International Game in London, England - Houston Texans vs Jacksonville Jaguars
  • Sunday, October 25, 2026: NFL International Game in Paris, France - Pittsburgh Steelers vs New Orleans Saints
  • Sunday, November 8, 2026: NFL International Game in Madrid, Spain - Cincinnati Bengals vs Atlanta Falcons
  • Tuesday, November 10, 2026: NFL Trade Deadline
  • Sunday, November 15, 2026: NFL International Game in Munich, Germany - New England Patriots vs Detroit Lions
  • Sunday, November 22, 2026: NFL International Game in Mexico City, Mexico - Minnesota Vikings vs San Francisco 49ers
  • Wednesday, November 25, 2026: Thanksgiving Eve Game - Green Bay Packers vs LA Rams
  • Thursday, November 26, 2026: Thanksgiving - Chicago Bears vs Detroit Lions, Philadelphia Eagles vs Dallas Cowboys and Kansas City Chiefs vs Buffalo Bills
  • Friday, November 27, 2026: Black Friday Game - Denver Broncos vs Pittsburgh Steelers
  • Thursday, December 24, 2026: Christmas Eve Game - Houston Texans vs Philadelphia Eagles
  • Friday, December 25, 2026: Christmas Day - Green Bay Packers vs Chicago Bears, Buffalo Bills vs Denver Broncos and LA Rams vs Seattle Seahawks
  • Sunday, January 10, 2027: NFL regular season ends
  • Saturday, January 16, 2027-Monday, January 18, 2027: Super Wild Card Weekend takes place
  • Saturday, January 23, 2027-Sunday, January 24, 2027: Divisional Round takes place
  • Sunday, January 31, 2027: AFC and NFC Conference Championship Games take place
  • Sunday, February 14, 2027: Super Bowl LXI takes place at SoFi Stadium in Inglewood, Californi